RNA motif discovery by SHAPE and mutational profiling (SHAPE-MaP)
نویسندگان
چکیده
منابع مشابه
Identifying RNA contacts from SHAPE-MaP by partial correlation analysis
In a recent paper Siegfried et al. 1 published a new sequence-‐based structural RNA assay that utilizes mutational profiling to detect base pairing (MaP). Output from MaP provides information about both pairing (via reactivities) and contact (via correlations). Reactivities can be coupled to partition function folding models for structural inference 2 , while correlations can reveal pairs of s...
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ژورنال
عنوان ژورنال: Nature Methods
سال: 2014
ISSN: 1548-7091,1548-7105
DOI: 10.1038/nmeth.3029